Item: BIO1801
Product: Acetyl-L-Carnitine (ALC) BiosintTM 500 mg Pharmaceutical Grade (120 Vegetarian Capsules)
Sale: $28.99 (Reg. $47.98)
Supplement Facts
Serving Size 1 Capsule
Servings Per Container 120
|
ONE CAPSULE PROVIDES Acetyl-L-Carnitine 500 mg* |
% Daily Value * |
Suggested usage: Take 2 - 3 capsules daily.
Acetyl-l-carnitine is a stabilized form of the amino acid metabolite L-Carnitine and is utilized in the same manner in the body. Acetyl-l-carnitine plays and important role in the transfer and utilization of long-chain fatty acids, which are used in the production of energy.
BiosintTM pharmaceutical grade Acetyl-L-Carnitine is manufactured in Italy by Sigma Tau Health Sciences which is the premier international clinical research organization for ALC and its uses.
NOTE: Beware of internet brands that claim "pharmaceutical grade acetyl-l-carnitine" but don't include name of manufacturer. There are only two manufacturers in the world who make pharmaceutical grade acetyl-l-carnitine. They are Sigma Tau Health Sciences (BiosintTM) and Lonza (L-CarnipureTM). Non-brand ALC is made in China and much less expensive.
Acetyl-L-Carnitine (ALC) Acetyl-l-carnitine is a molecule that occurs naturally in the brain, liver, and kidney. Natural levels of Acetyl-l-carnitine diminish as we age.
Common uses for supplemental Acetyl-l-carnitine:
Alzheimer's
The acetyl group that is part of acetyl-L-carnitine contributes to the production of the neurotransmitter acetylcholine, which is required for mental function. Several double-blind clinical trials suggest that acetyl-L-carnitine delays the progression of Alzheimer’s disease and enhances overall performance in some people with Alzheimer’s disease. Alzheimer’s research has been done with the acetyl-L-carnitine form, rather than the L-carnitine form, of this nutrient.
Several clinical trials have found that acetyl-L-carnitine supplementation delays the progression of Alzheimer’s disease, improves memory, and enhances overall performance in some people with Alzheimer’s disease. Overall, most short-term studies have shown clinical benefits, and most long-term studies (one year) have shown a reduction in the rate of deterioration.
Brain
One double-blind trial has found that acetyl-L-carnitine may be helpful for people with degenerative cerebellar ataxia, a loss of muscular coordination caused by disease in the cerebellum (the hind part of the brain that controls muscle tone and balance).
Several clinical trials suggest that acetyl-L-carnitine delays onset of ARCD and improves overall cognitive function in the elderly. In a controlled clinical trial, acetyl-L-carnitine was given to elderly people with mild cognitive impairment. After 45 days of acetyl-L-carnitine supplementation at 1,500 mg per day, significant improvements in cognitive function (especially memory) were observed. Another large trial of acetyl-L-carnitine for mild cognitive impairment in the elderly found that 1,500 mg per day for 90 days significantly improved memory, mood, and responses to stress. The favorable effects persisted at least 30 days after treatment was discontinued. Controlled and uncontrolled clinical trials on acetyl-L-carnitine corroborate these findings.
Depression
Acetyl-L-carnitine may be effective for depression experienced by the elderly. A preliminary trial found that acetyl-L-carnitine supplementation was effective at relieving depression in a group of elderly people, particularly those showing more serious clinical symptoms. These results were confirmed in another similar clinical trial. In that trial, participants received either 500 mg three times a day of acetyl-L-carnitine or a matching placebo. Those receiving acetyl-L-carnitine experienced significantly reduced symptoms of depression compared to those receiving placebo. At least two other clinical studies of acetyl-L-carnitine for depression in the elderly have reported similar results.
Drug interactions:
Are there any drug interactions? A. Didanosine (Depletion or interference) Didanosine is a drug that blocks reproduction of the human immunodeficiency virus (HIV). HIV is the virus that infects people causing acquired immunodeficiency syndrome (AIDS). Didanosine is used in combination with other drugs to treat HIV infection.
Acetyl-l-carnitine suggested dosage is 500 mg two to three times daily.
Other product related news:
Carnitine Supplement Helps Sperm Swim By David Douglas NEW YORK (Reuters Health) - Taking carnitine supplements seems to improve sperm mobility in men with poorly active sperm, a problem known as asthenozoospermia, Italian researchers report.
However, for carnitine to work, tiny structures within the cell called mitochondria must function properly. Mitochondria are important because they provide the energy needed for sperm to move their tail and "swim."
Senior investigator Dr. Carlo Foresta told Reuters Health that "it is well known that in some asthenozoospermic subjects an improvement of sperm (motion occurs) after carnitine administration...However in other asthenozoospermic patients this effect is not present."
To investigate further, Foresta of the University of Padua and colleagues studied 30 asthenozoospermic men divided into two groups depending on whether they had normal or abnormal mitochondria function. The researchers' findings appear in the medical journal Fertility & Sterility.
In patients with normal mitochondria function, movement rose from 29.3 percent before treatment to 41.1 percent after 3 months of carnitine. However, in those with abnormal function, movement held steady at about 24 percent.
Thus, Foresta concluded that carnitine treatment is useful "in ameliorating sperm motility only when optimal...mitochondrial function ... is conserved." SOURCE: Fertility & Sterility 2005.
Acetyl-L-Carnitine, ALC, Acetylcarnitine, ALCAR
Acetyl-L-Carnitine 500 mg & R-Alpha Lipoic Acid 100 mg combination $43.91
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